16 Oct 09 Testofen Boosts Testosterone

Gencor, the company that makes Testofen, has published human clinical trials that shoe the fenugreek extract boosts testosterone dramatically.

• Improves libido and erectile dysfunction (rat)
• Has anabolic and androgenic effects (rat)
• Increases bio-available free testosterone (human)

Tags: Erectile Dysfunction, libido

24 Nov 08 Tongat Ali, especially the LJ100, Increased Sex Drive

You will be very pleased with my results of taking tongat ali, especially the LJ100.  I have experienced tremendous improvements in tone and overall body mass. Above I linked the Wikipedia page that is actually very informative.

A big “side effect” that I have personally noticed is an increased sex drive. LJ100 ™ is an extremely high quality 100:1 standardized Tongkat Ali extract. We guarantee this product to be the highest quality LJ100.

Tongkat Ali is the popular folk name for Eurycoma Longifolia, a medium sized, slender rain forest tree. The name Tongkat Ali means Ali’s walking stick and the plant is native to Malaysia, lower burma, Thailand and Indonesia. Tongkat Ali enjoys a history of use that dates back to the 1700’s, and today there is a growing body of serious science that corroborates its traditional uses, specifically for the patented and proprietary brand LJ100 Tongkat Ali standardized extract containing 28% bioactive glycopeptides.

LJ100 Tongkat Ali in Testyx TPL

LJ100 is a proprietary, patented ingredient, and has become recognized as the premier brand of Eurycoma Longifolia for supplements that build and tone muscles, boost energy levels, decrease body fat, slow the aging process, and increase libido for health-conscious consumers. LJ100 has undergone an exclusive, patented extraction process to capture the most potent, biologically active compounds. SourceOne Global Partners, headquarters in Chicago, holds the exclusive distribution rights to market and sell LJ100 Tongkat Ali in dietary supplements.

ATP and Lean Muscle

In studies, LJ100 Tongkat Ali extract greatly increases ATP production. ATP, or adenosine triphosphate, is the basic unit of energy in the body, responsible for keeping us alive and going. By increasing ATP, overall energy and vitality are increased. Most people seek more energy and LJ100 Tongkat Ali provides it, without hyper stimulation, jittery nerves or insomnia. Promoting human energy production is a valuable health benefit by itself to make LJ100 Tongkat Ali an enduring botanical superstar. People want energy more than just about any other functional attribute.

Endocrinologists have known for a long time that testosterone increases the body’s ratio of lean muscle mass to fat. In both animals and humans, LJ100 Tongkat Ali increases muscle mass. In a study of men, half the subjects ingested LJ100 and half did not. In an eight-week physical training program the men who consumed LJ100 experienced greater gains in muscle mass and strength than those that did not. This demonstrates the powerful anabolic properties of Tongkat Ali. Instead of turning to the use of dangerous and potentially lethal steroids, it is recommended that more athletes opt for Tongkat Ali. In Malaysia, many professional field hockey players use LJ100 Tongkat Ali as an androgen and swear to its performance-enhancing effects. According to Chris Kilham, ethno botanist, author and lecturer, in a recent article in Physical Magazine,. “LJ100 Tongkat Ali has potential to revolutionize the sport nutrition category.”

Tags: LJ100, Testosterone, Testyx TPL, Tongkat Ali

24 Nov 08 Testosterone Stroke Research

Age-dependent effects of testosterone in experimental stroke

This research was funded by US Public Health Service grants NS049210 and NS33668 and American Heart Association Grant 0825526G.

Jian Cheng¹, Weidong Hu², Thomas J Toung², Zhizheng Zhang¹, Susan M Parker¹, Charles E Roselli^1,3 and Patricia D Hurn^1,3,4

Tags: aging, androgen receptor, aromatase, cerebral ischemia, stroke, Testosterone, Testosterone effects

24 Nov 08 Testosterone Replacement Therapy News 11/24/2008

Testosterone Replacement Therapy

Testosterone Replacement Therapy

Testosterone replacement should in theory approximate the natural, endogenous production of the hormone. The average male produces 4-7 mg of testosterone per day in a circadian pattern, with maximal plasma levels attained in early morning and minimal levels in the evening.8 However, the subtleties of pulsatile and diurnal rhythms are potentially difficult to imitate, and evidence suggests that different dose response curves exist for different androgen-dependent functions.9 The clinical rationale for treatment of testosterone deficiency may include:
-stabilizing or increasing bone density
-enhancing body composition by increasing muscle strength and reducing adipose
-improving energy and mood
-maintaining or restoring secondary sexual characteristics, libido and erectile function

Types of Testosterone Replacement Therapy

Ideal testosterone replacement therapy produces and maintains physiologic serum concentrations of the hormone and its active metabolites without significant side effects or safety concerns. Several different types of testosterone replacement are currently marketed, including tablets, injectables, and transdermal systems.

Oral agents

Although elevations in liver function tests and abnormalities at liver scan and biopsy are relatively common in patients receiving oral testosterone,10 these preparations still constitute roughly a third of the testosterone prescriptions filled in the United States. Both modified and unmodified oral testosterone preparations are available. Unmodified testosterone is rapidly absorbed by the liver, making satisfactory serum concentrations difficult to achieve. Modified 17-alpha alkyltestosterones, such as methyltestosterone or fluoxymesterone, also require relatively large doses that must be taken several times a day.

Intramuscular injection

Testosterone cypionate and enanthate are frequently used parenteral preparations that provide a safe means of hormone replacement in hypogonadal men. Testosterone is esterified to inhibit degradation and to make it soluble in oil-based injection vehicles that retain the drug in muscle tissue. In men 20-50 years of age, an intramuscular injection of 200 to 300 mg testosterone enanthate is generally sufficient to produce serum testosterone levels that are supranormal initially and fall into the normal ranges over the next 14 days. Fluctuations in testosterone levels may yield variations in libido, sexual function, energy, and mood. Some patients may be inconvenienced by the need for frequent testosterone injections.11 Increasing the dose to 300 to 400 mg may allow for maintenance of eugonadal levels of serum testosterone for up to three weeks, but higher doses will not lengthen the eugonadal period.12

Transdermal systems

Currently, three testosterone transdermal systems are marketed: a system applied to the scrotum that has no permeation enhancers [Testoderm, 6 mg, ALZA Corporation, Palo Alto, CA] and two systems that contain permeation enhancers for application to appendage or torso skin [Androderm 2.5 mg and 5 mg, SmithKline Beecham Pharmaceuticals, Philadelphia, PA; Testoderm TTS, 5 mg, ALZA Corporation, Palo Alto, CA]. Scrotal patches produce high levels of circulating dihydrotestosterone (DHT) due to the high 5-alpha-reductase enzyme activity of scrotal skin.

Clinical studies of transdermal systems demonstrate their efficacy in providing adequate testosterone replacement therapy.13-15 Skin irritation may be associated with the use of transdermal systems; however, Testoderm and Testoderm TTS caused significantly less topical skin irritation than Androderm in two separate clinical studies.16,17

From Web MD

Erectile Dysfunction: Testosterone Replacement Therapy

Inadequate production of testosterone is not a common cause of erectile dysfunction; however, when ED does occur due to decreased testosterone production, testosterone replacement therapy may improve the problem.

Tags: Erectile Dysfunction, testosterone replacement

20 Nov 08 Testosterone May Affect Atherosclerosis

Estrogen, Testosterone May Affect Atherosclerosis

Doctors may eventually check sex hormones to assess heart disease risk

By David March
Johns Hopkins Medicine

Naturally produced sex hormones may influence the risk and progression of atherosclerosis, or hardening of the arteries, Johns Hopkins researchers report in a recent study. The findings may help explain the increased risk men have of developing heart disease, which runs about twofold higher than women’s heart disease risk worldwide.

The study suggests that older women who produce a relatively high amount of estrogen are more likely to develop coronary artery calcium, or CAC, a component of the fatty plaque that builds up in blood vessels and hardens arteries. Older men with relatively high amounts of testosterone are also more likely to develop CAC. However, once CAC is present, higher testosterone appears to help prevent CAC from progressing too quickly in men’s arteries. These findings were presented Nov. 11 at the American Heart Association’s annual Scientific Sessions in New Orleans.

“We know many things that increase the risk of cardiovascular disease, such as high cholesterol and diabetes,” said Erin D. Michos, assistant professor of medicine at the Johns Hopkins University School of Medicine and its Heart and Vascular Institute, in an interview. “But 10 percent to 20 percent of people who get heart disease don’t have these risk factors, so we need to understand other factors that might be involved. Our results suggest that someday, in addition to testing your cholesterol and blood sugar levels to assess your heart disease risk, your doctor may want to measure your sex hormone levels.”

The study assessed whether sex hormones affect the risk of atherosclerosis using data from the Multi-Ethnic Study of Atherosclerosis, or MESA, an ongoing study that’s been tracking 6,814 patients of four different races since 2000 to determine factors that influence risk of developing cardiovascular disease. The MESA study recruited healthy people from six communities across the United States. Through a baseline assessment and regular checkups, researchers track each volunteer to learn what factors affect a person’s risk of developing cardiovascular disease or progressing once the disease develops.

For the Johns Hopkins study, researchers used data from 2,700 male and 1,646 postmenopausal female MESA participants who did not use hormone replacement therapy. At the beginning of the study, participants answered detailed questionnaires about their demographics and medical history, and they received a basic health assessment measuring their height, weight and blood pressure. Participants also received a CT scan measuring their baseline level of CAC and had their blood drawn to measure blood concentrations of various sex hormones, including estradiol, the dominant type of estrogen in women, and testosterone, the dominant sex hormone in men. About half the participants had a second CT scan 18 months later. The other half had their second scan 37 months after the initial scan.

Taking into account factors known to affect atherosclerosis risk, such as age, body mass index, blood pressure, and exercise and smoking habits, Michos and her colleagues assessed whether there was a correlation between changes in CAC between patients’ two scans and their levels of sex hormones. In women who had no baseline CAC, the researchers found that women with higher amounts of estrogen were 30 percent more likely to develop CAC by their second scan than women with lower levels of estrogen. This risk was most pronounced in women older than 65. Levels of estrogen did not seem to significantly affect whether CAC increased in women who already had CAC at baseline.

In those men who had no CAC at baseline, the researchers found that men with higher testosterone levels were 48 percent more likely to develop CAC than those with the lowest testosterone levels, with the risk greatest among men older than 55. In men who already had CAC at baseline, higher testosterone levels appeared to have a protective effect, reducing the chances that CAC measurements would increase at follow-up.

Michos added that the role that sex hormones play in cardiovascular disease is complex, with often diverse and contradictory effects. While the Johns Hopkins study looked at early atherosclerosis in the coronary arteries, sex hormones may also affect heart disease risk through other mechanisms, including influencing inflammation, blood clotting and whether blood vessels are constricted or relaxed. In the future, she and her colleagues plan to study how sex hormone levels might affect the risk of specific cardiovascular incidents, such as heart attacks and strokes, in men and women.

MESA is funded by the National Heart, Lung and Blood Institute, a member of the National Institutes of Health.

Other researchers who participated in this study are Dhananjay Vaidya, Sherita Hill Golden and Pamela Ouyang, all of Johns Hopkins; Susan R. Heckbert, of the University of Washington; and Mary Cushman, of the University of Vermont.

Tags: atherosclerosis

16 Nov 08 What is testosterone?

What is testosterone?

Testosterone is a substance produced in the testes and in the adrenal glands that helps to build protein and is essential for normal sexual behaviour and the development of masculine characteristics such as a deep voice, broad shoulders, and hair growth.

It also affects many metabolic activities, such as production of blood cells in the bone marrow, bone formation, fat metabolism, carbohydrate metabolism, liver function and prostate gland growth. Additionally, normal testosterone levels maintain energy level, good mood, fertility and sexual desire

Low testosterone levels are typically defined as less than 300ng/dL (nanograms per decilitre) of total testosterone and less than 5ng/dL of free testosterone.

Tags: free testosterone, What is testosterone?

13 Nov 08 Testofen® Boost Free Testosterone

Testofen® is a not-so-well-known herb… but it’s become quite an underground sensation for many European bodybuilders. It contains a variety of powerful anabolic compounds, among them Protodioscin and Steroidal Saponins.

Unlike other natural testosterone-boosting herbs, Testofen® contains a host of active compounds in addition to Protodioscin and Saponins—all responsible for significantly boosting Testosterone levels, muscle mass, and libido.

Research suggests the majority of these saponins exist as saponin glycosides. Fenuside is a set of potent saponin glycosides unique to Testofen® that have been specially extracted and standardized to yield the highest potency and purity for maximal benefit.

Now, since Testofen® is the only natural substance that produces these unique Fenusides, what’s interesting is Testofen® “acts” more like Testosterone by binding to the Testosterone receptor sites and creating more Testosterone. And as a result, it amplifies the androgenic and anabolic activity in the body.

Equally important, though, it does this without shutting off the body’s own natural production of Testosterone. In a recent randomized, placebo-controlled clinical trial with 60 men, Testofen® nearly doubled (+98%) users’ Testosterone. In yet another study, Testofen® was compared to a “real” anabolic steroid, and it faired exceptionally well—comparable in muscle mass gains after only 14 days of use, with a fraction of the amount of Testosterone produced in the body by the “real” deal.

It’s for these reasons, Testofen® is one of bodybuilding’s best-kept secrets because, as confirmed by multiple research studies, it demonstrates strong androgenic and anabolic properties to boost libido and increase muscle mass.

Tags: Boost Free Testosterone, Testofen