Male Menopause Negatively Affects Millions of Men

When testosterone levels start falling, males can easily encounter substantial emotional and physiological changes. Low testosterone levels most often goes undiagnosed and therefore without therapy. Low testosterone levels signs and symptoms can interfere with a man’s well being and should not be ignored.

Medical professionals look at testosterone variations as a normal aspect of getting older. But is this “normal” good for a man who may live another thirty or forty years. A man’s experience hormone decline are different from what women typically experience. A man’s androgenic hormone or testosterone levels decrease more slowly, with testosterone levels dropping around one percent each year beginning in their late thirties.

Male Menopause Lowers Testosterone

Lower testosterone levels responsible for reduced sexual prowess, tiredness, and putting on extra weight. Are you experiencing unwanted weight gain, an inability to concentrate, lack of productivity, moodyness, low libido and unexplained aches and pains? Males can be affected from birth with problems caused by low testosterone levels because of genetic factors.

Male Hormone Replacement

So what are the treatments for male hypogonadism caused by low testosterone include hormone replacement therapy testosterone replacement therapy (TRT). Men can use physician prescribed testosterone pellet implants, topical gels, patches, and injections. Some of these medications are actually synthetic analogs of the testosterone molecule produced by humans while others are identical in structure and are referred to as bio-identical testosterone. Low “T” levels have been associated to serious medical disorders like as high cholesterol, impotence, having diabetes and heart disease.

Lower "T" Levels Negatively Affect

Lower levels of testosterone blamed for reduced sexual prowess, fatigue, sadness, and weight gain. While most frequently may be linked with women’s health, age-related hormone changes, often dubbed menopause, can occur in men as well, causing symptoms of fatigue, mood swings, decreased desire for sex, hair loss, lack of concentration and weight gain. The study says 5 million men are suffering from healthtroubles related to a natural decline in androgen hormone or testosterone, but the facts say that may be just the tip of the iceberg.

Testosterone Levels Effect You

Male hypogonadism, takes place when the testicles do not produce ample the male hormone, testosterone, the hormone that which is important for making a man, manly. When hormone levels fall, males encounter significant cerebral and physical changes. This disorder most often goes undiagnosed and therefore without therapy. Signs and symptoms can interfere with a man’s total well being and should not be ignored.

Doctors believe that when a man is about seventy, the decrease in a man’s testosterone level could be up to fifty percent or more compared to baseline levels. It must also be noted that old men are not the only ones at risk. Males can be affected from birth with problems caused by low testosterone levels because of genetic factors.

Testosterone Treatment

Males report feeling better quickly once they begin testosterone treatment.They say their energy levels shoot back to levels they haven’t experienced in decades. They report that they have gotten strength and mental acuity again. That ‘zest for life” has returned. Low “T” levels have been associated to severe medical disorders like as high cholesterol, erection dysfunction, diabetes and cardiovascular disease.

Testosterone Replacement Therapy

Testosterone replacement should in theory approximate the natural, endogenous production of the hormone. The average male produces 4-7 mg of testosterone per day in a circadian pattern, with maximal plasma levels attained in early morning and minimal levels in the evening.8 However, the subtleties of pulsatile and diurnal rhythms are potentially difficult to imitate, and evidence suggests that different dose response curves exist for different androgen-dependent functions.9 The clinical rationale for treatment of testosterone deficiency may include:
-stabilizing or increasing bone density
-enhancing body composition by increasing muscle strength and reducing adipose
-improving energy and mood
-maintaining or restoring secondary sexual characteristics, libido and erectile function

Types of Testosterone Replacement Therapy

Ideal testosterone replacement therapy produces and maintains physiologic serum concentrations of the hormone and its active metabolites without significant side effects or safety concerns. Several different types of testosterone replacement are currently marketed, including tablets, injectables, and transdermal systems.

Oral agents

Although elevations in liver function tests and abnormalities at liver scan and biopsy are relatively common in patients receiving oral testosterone,10 these preparations still constitute roughly a third of the testosterone prescriptions filled in the United States. Both modified and unmodified oral testosterone preparations are available. Unmodified testosterone is rapidly absorbed by the liver, making satisfactory serum concentrations difficult to achieve. Modified 17-alpha alkyltestosterones, such as methyltestosterone or fluoxymesterone, also require relatively large doses that must be taken several times a day.

Intramuscular injection

Testosterone cypionate and enanthate are frequently used parenteral preparations that provide a safe means of hormone replacement in hypogonadal men. Testosterone is esterified to inhibit degradation and to make it soluble in oil-based injection vehicles that retain the drug in muscle tissue. In men 20-50 years of age, an intramuscular injection of 200 to 300 mg testosterone enanthate is generally sufficient to produce serum testosterone levels that are supranormal initially and fall into the normal ranges over the next 14 days. Fluctuations in testosterone levels may yield variations in libido, sexual function, energy, and mood. Some patients may be inconvenienced by the need for frequent testosterone injections.11 Increasing the dose to 300 to 400 mg may allow for maintenance of eugonadal levels of serum testosterone for up to three weeks, but higher doses will not lengthen the eugonadal period.12

Transdermal systems

Currently, three testosterone transdermal systems are marketed: a system applied to the scrotum that has no permeation enhancers [Testoderm, 6 mg, ALZA Corporation, Palo Alto, CA] and two systems that contain permeation enhancers for application to appendage or torso skin [Androderm 2.5 mg and 5 mg, SmithKline Beecham Pharmaceuticals, Philadelphia, PA; Testoderm TTS, 5 mg, ALZA Corporation, Palo Alto, CA]. Scrotal patches produce high levels of circulating dihydrotestosterone (DHT) due to the high 5-alpha-reductase enzyme activity of scrotal skin.

Clinical studies of transdermal systems demonstrate their efficacy in providing adequate testosterone replacement therapy.13-15 Skin irritation may be associated with the use of transdermal systems; however, Testoderm and Testoderm TTS caused significantly less topical skin irritation than Androderm in two separate clinical studies.16,17

From Web MD

Erectile Dysfunction: Testosterone Replacement Therapy

Inadequate production of testosterone is not a common cause of erectile dysfunction; however, when ED does occur due to decreased testosterone production, testosterone replacement therapy may improve the problem.